The Gender Program of Central Ohio was established in 1979, following ad hoc efforts to meet the needs of gender variant people in central Ohio and surrounding regions dating to 1975. The GPCO serves the needs of individuals who wish to transition gender roles with or without hormones, and with or without sexual reassignment surgery (SRS).

The GPCO is dedicated to a non-dogmatic approach. It respects the individual's special circumstances and treats each person's condition as unique, while at the same time adhering to the treatment guidelines set by the International Standards of Care (SOC). Conforming to the SOC makes it easier for GPCO members to access other programs and specialists whose expertise may be needed to help with the transition process. It is the professional responsibility of the GPCO to keep up with developments in research and clinical practice. This means attending professional meetings, reviewing current literature, and keeping track of other gender dysphoria clinics and centers. The GPCO is dedicated to developing and maintaining reciprocity with centers across the country and around the world so that program participants have the widest range of choices for completing treatment. In addition to direct counseling, the GPCO can make calls or write letters to family, employers, coworkers, physicians, and attorneys (upon your request only).